By John H. Scholefield, Cathy Eng

Colorectal melanoma: prognosis and scientific Management offers colorectal surgeons, gastroenterologists and oncologists with an authoritative, functional consultant to most sensible perform within the prognosis and medical administration of colorectal cancer.

Covering all sorts of remedy together with surgical procedure, chemotherapy and radiotherapy, it examines some of the new and rising cures, new thoughts for screening and prevention, in addition to the newest advice at the such a lot demanding and debatable elements of handling colorectal cancer.

The authors current vital info on:

  • Controversies in adjuvant chemotherapy
  • Long as opposed to brief path radiotherapy
  • Minimally invasive surgical procedure and robotics
  • Radical colonic resection

Each bankruptcy comprises key issues, assistance and tips and scientific case reports to help fast shopping and information of the fundamental rules, whereas self-assessment questions permit readers to check their scientific knowledge.

With major foreign surgeons, gastroenterologists and oncologists combining to provide their massive wealth of craftsmanship and information, Colorectal Cancer is a well-balanced, integral source for all these interested by colorectal melanoma management. 


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Extra info for Colorectal Cancer: Diagnosis and Clinical Management

Sample text

The importance of these two studies is that they demonstrate beyond doubt that endoscopy and polypectomy can reduce the incidence of colorectal cancer and that FS is a credible candidate as a first line screening test. Indeed, in England, a commitment has been made to roll-out ‘once only’ FS as a screening modality between the ages of 55 and 60 prior to the commencement of FOBT screening. There remains a significant question around uptake of FS screening. Because the UK Flexiscope and the SCORE trials were performed in volunteers, the population uptake of FS is unknown.

Once-only flexible sigmoidoscopy and onceonly colonoscopy indicated that the uptake for colonoscopy was significantly lower than for either FIT or flexible sigmoidoscopy [56]. It is also interesting to note that the effect of colonoscopy in reducing colorectal cancer mortality and incidence is much stronger for the left side of the colon than for the right side of the colon [57–59]. This is presumably associated with the quality of colonoscopy; bowel preparation is often poorer in the right colon than the left colon and adenomas in the right colon are often flat and subtle when compared with the polypoid lesions seen more commonly on the left.

58 Ma J, Pollak MN, Giovannucci E, Chan JM, Tao Y, Hennekens CH, et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 1999 Apr 7; 91(7): 620–5. 59 Ma J, Giovannucci E, Pollak M, Leavitt A, Tao Y, Gaziano JM, et al. A prospective study of plasma C-peptide and colorectal cancer risk in men. J Natl Cancer Inst 2004 Apr 7; 96(7): 54–53. 60 Dehal AN, Newton CC, Jacobs EJ, Patel AV, Gapstur SM, Campbell PT.

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